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Study identifier: NCT05531474 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Bariatric Surgery for the Reduction of cArdioVascular Events Randomized Controlled Trial

Condition: Cardiovascular Complication · Bariatric Surgery Candidate  ·  Sponsor: Population Health Research Institute

PhaseNA
Planned participants700
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

The primary objective of this study is to evaluate if, in patients with severe obesity (body mass index (BMI) ≥30 kg/m2) and high-risk cardiovascular disease (CVD), bariatric surgery compared to medical weight management (MWM) safely reduces the risk of major cardiovascular events. The cost-effectiveness of bariatric surgery will also be examined. Separate sub-studies will be performed to examine the relationship between bariatric surgery and mental health and cognition (BRAVE-Mind), cardiac structure and function, genomics, proteomics and metabolomics.

This description comes directly from the study's public registry record.

Talk to the study team

Jorge Wong, MD, MPH, FRCPC  ·  905-521-2100  ·  jorge.wong@phri.ca

Sumathy Rangarajan, MSc  ·  905-296-5792  ·  sumathy.rangarajan@phri.ca

Always discuss trial participation with your own doctor first.

Locations (1)

Hamilton Health SciencesHamilton, Ontario, CanadaRecruiting

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Source record: clinicaltrials.gov/study/NCT05531474