Condition: Irritable Mood · Sponsor: University Hospital, Montpellier
Irritability is defined as developmentally inappropriate proneness to anger. Irritability is a symptom of several mental health conditions in children and adolescents such as attention deficit hyperactivity disorder (ADHD), oppositional defiant disorder (ODD), conduct disorder (CD), depressive disorders, anxiety disorders.Irritability has been associated with poor functional outcomes across the lifespan and was found to be specifically associated with concurrent and longitudinal emotional disorders, suicidality and impaired academic and socio-professional functioning. Children with high irritability also have distinct physiological profiles with hyper-reactivity to stress and perceived threats. Despite the high prevalence and health issues related to irritability, there is little treatment research on this topic. Developing evidence-based non-pharmacological treatment options for children suffering from severe, chronic irritability is therefore a particularly important target for clinical research.
This description comes directly from the study's public registry record.
Diane Pr PURPER-OUAKIL · 04.67.33.60.09 · d-purper_ouakil@chu-montpellier.fr
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| UH of Montpellier | Montpellier, France | Recruiting |
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Source record: clinicaltrials.gov/study/NCT05528926