← Eichor
Study identifier: NCT05525507 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Delayed Immunological Tolerance in Patients With Well-functioning Pre-existing HLA-matched Kidney Transplants

Condition: End Stage Kidney Disease · Immunological Tolerance · Kidney Transplant Failure and Rejection  ·  Sponsor: University of California, Los Angeles

PhasePhase 1
Planned participants10
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersYes

About this study

The study seeks to determine if patients with a pre-existing, well-functioning kidney transplant from a HLA-identical living donor can be withdrawn from immunosuppressive medications without compromising allograft function through hematopoietic stem cell (HPSC) infusion from the same donor. HPSC infusion will be preceded by a conditioning regimen of total lymphoid irradiation (TLI) and rabbit anti-thymocyte globulin (rATG).

This description comes directly from the study's public registry record.

Talk to the study team

Ruth Wynne Jones  ·  424-402-9564  ·  rwynnejones@mednet.ucla.edu

Jenny Lester, MPH  ·  310-794-9728  ·  jlester@mednet.ucla.edu

Always discuss trial participation with your own doctor first.

Locations (1)

UCLALos Angeles, California, United StatesRecruiting

Follow this study

Get one email when the public record changes — results posted, or the study's status changes. Nothing else, ever.

We email about this public record only. Unsubscribe anytime with one click. Never medical advice.

Is this your study? This page was generated automatically from the public registry record. Sponsors can claim it — free — to add branding and verified contact routing. Claim this page →

This page is independently generated by Eichor from the public ClinicalTrials.gov record and re-synced daily. It is not the sponsor's official website unless claimed. Nothing here is medical advice; eligibility is always determined by the study team — talk to your own doctor first.

Source record: clinicaltrials.gov/study/NCT05525507