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Study identifier: NCT05519579 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Intrathecal Chemoprophylaxis to Prevent Neurotoxicity Associated With Blinatumomab Therapy for Acute Lymphoblastic Leukemia

Condition: Acute Lymphoblastic Leukemia  ·  Sponsor: Northside Hospital, Inc.

PhasePhase 2
Planned participants20
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

Changing the schedule of intrathecal chemotherapy to be given before and during blinatumomab will maintain the anti-leukemic effects of this drug while at the same time adding the benefit of limiting the neurotoxicity associated with cytokine release.

This description comes directly from the study's public registry record.

Talk to the study team

Caitlin Guzowski  ·  404-851-8523  ·  caitlin.guzowski@northside.com

Always discuss trial participation with your own doctor first.

Locations (1)

Northside HospitalAtlanta, Georgia, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT05519579