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Study identifier: NCT05514015 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Clinical Study of Rituximab Combined With Corticosteroids or Rituximab Monotherapy in the Treatment of Primary Membranous Nephropathy

Condition: Primary Membranous Nephropathy  ·  Sponsor: First Affiliated Hospital, Sun Yat-Sen University

PhasePhase 4
Planned participants78
Who can joinAll sexes, 18 Years to 75 Years
Healthy volunteersNo

About this study

This was a prospective, randomized, multicenter clinical trial. Seventy-eight patients with primary membranous nephropathy (PMN) were randomly divided into intervention or control group. Intervention group was given rituximab combined with corticosteroids in induction therapy and the control group was given rituximab monotherapy. After 6 months, patients who had decreased 24h urinary protein by \> 25% but did not achieve CR were given rituximab maintenance therapy. The complete response rate at 12 months was measured.

This description comes directly from the study's public registry record.

Talk to the study team

Wei Chen  ·  8602087769673  ·  chenwei99@mail.sysu.edu.cn

Qiong Wen  ·  8602087769673  ·  wenqiong@mail.sysu.edu.cn

Always discuss trial participation with your own doctor first.

Locations (1)

Wei ChenGuangzhou, Guangdong, ChinaRecruiting

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Source record: clinicaltrials.gov/study/NCT05514015