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Study identifier: NCT05512286 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Patient-Reported Outcome and Safety Between Preoperative and Postmastectomy Radiotherapy in DIEP Flap Reconstruction

Condition: Breast Cancer  ·  Sponsor: Fudan University

PhaseNA
Planned participants80
Who can joinFemale, 18 Years to no upper limit
Healthy volunteersNo

About this study

This study is the first prospective randomized study assessing the patient-reported outcomes and safety outcomes between preoperative and postmastectomy radiotherapy in locally advanced breast cancer patients with immediate reconstruction of deep inferior epigastric perforator(DIEP) flap. Radiotherapy before mastectomy and autologous free-flap breast reconstruction can avoid adverse radiation effects on healthy donor tissues and delays to adjuvant radiotherapy. We aimed to explore the feasibility of preoperative radiotherapy followed by DIEP flap reconstruction in patients with breast cancer requiring mastectomy.

This description comes directly from the study's public registry record.

Talk to the study team

Jiong Wu  ·  862164175590  ·  wujiong1122@vip.sina.com

Shuang Hao  ·  862164175590  ·  hzz50@hotmail.co,

Always discuss trial participation with your own doctor first.

Locations (6)

Guangxi Provincial Cancer HospitalNanning, Guangxi, ChinaRecruiting
Henan Provincial Cancer HospitalZhengzhou, Henan, ChinaRecruiting
Hunan Provincial Cancer HospitalChangsha, Hunan, ChinaRecruiting
Huashan Hospital of Fudan UniversityShanghai, Shanghai Municipality, ChinaRecruiting
Yunnan Provincial Cancer HospitalKunming, Yunnan, ChinaRecruiting
Zhejiang Provincial Cancer HospitalHangzhou, Zhejiang, ChinaRecruiting

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Source record: clinicaltrials.gov/study/NCT05512286