← Eichor
Study identifier: NCT05511363 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

A Study to Assess Efficacy and Safety of KarXT for the Treatment of Psychosis Associated With Alzheimer's Disease (ADEPT-1)

Condition: Psychosis Associated With Alzheimer's Disease  ·  Sponsor: Karuna Therapeutics, Inc., a Bristol Myers Squibb company

PhasePhase 3
Planned participants410
Who can joinAll sexes, 55 Years to 90 Years
Healthy volunteersNo

About this study

This is a Phase 3, 38-week, randomized, double-blind, placebo-controlled, multicenter, outpatient study in subjects with psychosis associated with Alzheimer's Disease. The primary objective of the study is to evaluate relapse prevention in subjects with psychosis associated with Alzheimer's Disease treated with KarXT compared to placebo. The secondary objectives of the study are to evaluate the time from randomization to discontinuation for any reason or relapse and safety and tolerability in subjects with psychosis associated with Alzheimer's Disease treated with KarXT compared to placebo.

This description comes directly from the study's public registry record.

Talk to the study team

BMS Clinical Trials Contact Center www.BMSClinicalTrials.com  ·  855-907-3286  ·  Clinical.Trials@bms.com

First line of the email MUST contain NCT # and Site #.

Always discuss trial participation with your own doctor first.

Locations (129)

Local Institution - 1029Homewood, Alabama, United StatesActive Not Recruiting
Local Institution - 1044Phoenix, Arizona, United StatesCompleted
Local Institution - 1033Encino, California, United StatesCompleted
Local Institution - 1031Irvine, California, United StatesWithdrawn
ATP Clinical Research-302 W La Veta AveOrange, California, United StatesRecruiting
Local Institution - 1043Pasadena, California, United StatesCompleted
Local Institution - 1047San Marcos, California, United StatesCompleted
Sunwise Clinical Research, LLC - Walnut Creek - IVY - PPDSWalnut Creek, California, United StatesRecruiting
Local Institution - 1014Colorado Springs, Colorado, United StatesCompleted
Local Institution - 1013Stamford, Connecticut, United StatesCompleted
Local Institution - 1011Boca Raton, Florida, United StatesCompleted
Local Institution - 1020Bonita Springs, Florida, United StatesCompleted

+ 117 more locations — full list on the registry record.

Follow this study

Get one email when the public record changes — results posted, or the study's status changes. Nothing else, ever.

We email about this public record only. Unsubscribe anytime with one click. Never medical advice.

Is this your study? This page was generated automatically from the public registry record. Sponsors can claim it — free — to add branding and verified contact routing. Claim this page →

This page is independently generated by Eichor from the public ClinicalTrials.gov record and re-synced daily. It is not the sponsor's official website unless claimed. Nothing here is medical advice; eligibility is always determined by the study team — talk to your own doctor first.

Source record: clinicaltrials.gov/study/NCT05511363