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Study identifier: NCT05506085 Synced from ClinicalTrials.gov · July 28, 2026
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Deep Brain Stimulation for Laryngeal Dystonia: From Mechanism to Optimal Application

Condition: Laryngeal Dystonia · Adductor Spastic Dysphonia of Dystonia  ·  Sponsor: Indiana University

PhaseN/A
Planned participants12
Who can joinAll sexes, 18 Years to 70 Years
Healthy volunteersNo

About this study

Deep Brain Stimulation (DBS) is a neurosurgical procedure used to treat tremors, and dystonia. This study will enroll people who have a form of focal dystonia that affects their vocal cords called Adductor Laryngeal dystonia (ADLD). Participants will undergo Deep Brain Stimulation surgery to treat laryngeal dystonia as part of their clinical care. Before surgery, as part of the study they will have specialized testing to study the movement of the vocal cords, as well as functional magnetic resonance imaging (fMRI). While in the operating room, researchers will examine brain waves to better understand how faulty brain firing patterns lead to dystonia. After surgery, and activation of the deep brain stimulator, participants will repeat speech testing and vocal cord imaging as well as magnetic resonance imaging (MRI).

This description comes directly from the study's public registry record.

Talk to the study team

Rita Patel, PhD  ·  8128553886  ·  patelrir@iu.edu

S. Elizabeth Zauber, MD  ·  317-963-7437  ·  szauber@iupui.edu

Always discuss trial participation with your own doctor first.

Locations (1)

Indiana UniversityIndianapolis, Indiana, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT05506085