← Eichor
Study identifier: NCT05505357 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Omission of Breast Surgery for Breast Cancer Patients With pCR on MRI and Vacuum-assisted Biopsy After NST (OPTIMIST)

Condition: Breast Cancer Invasive  ·  Sponsor: Seoul National University Hospital

PhaseNA
Planned participants533
Who can joinFemale, 20 Years to no upper limit
Healthy volunteersNo

About this study

A prospective, multicenter, single-arm non-inferiority trial to demonstrate that breast cancer patients who are predicted to have a pathologic complete response on MRI and vacuum-assisted biopsy after neoadjuvant systemic therapy, and are omitted breast surgery have a non-inferior 5-year disease-free survival compared to those who had received breast surgery.

This description comes directly from the study's public registry record.

Talk to the study team

Han-Byoel Lee  ·  +82-2-2072-3447  ·  hblee80@gmail.com

Hong-Kyu Kim  ·  +82-2-2072-2980  ·  hkkim4592@gmail.com

Always discuss trial participation with your own doctor first.

Locations (1)

Seoul National University HospitalSeoul, South KoreaRecruiting

Follow this study

Get one email when the public record changes — results posted, or the study's status changes. Nothing else, ever.

We email about this public record only. Unsubscribe anytime with one click. Never medical advice.

Is this your study? This page was generated automatically from the public registry record. Sponsors can claim it — free — to add branding and verified contact routing. Claim this page →

This page is independently generated by Eichor from the public ClinicalTrials.gov record and re-synced daily. It is not the sponsor's official website unless claimed. Nothing here is medical advice; eligibility is always determined by the study team — talk to your own doctor first.

Source record: clinicaltrials.gov/study/NCT05505357