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Study identifier: NCT05505188 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Predictive and Impact of Pain After 6 Months of Radiotherapy, in Head and Neck Cancer

Condition: Neuropathic Pain · Anxiety Disorder/Anxiety State · Pain, Chronic  ·  Sponsor: University Hospital, Caen

PhaseNA
Planned participants120
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

Head and neck cancers are a source of complications and after-effects related to the disease and treatment. These cancers and their treatment alter the quality of life of patients and generate pain with physical and psychological components. Chronic pain affects 36% of patients at 6 months and 30% after this period. These pains are responsible for the consumption of level II and III analgesics in 53% of these patients. At the same time, after the end of treatment, nearly a quarter of patients continued to smoke and half still consumed alcohol at least twice a week. The hypothesis of this research is to investigate the correlation between pain and the continuation of addictions, the occurrence of depressive states, asthenia and the alteration of the patients' global quality of life. The investigators propose a two-center prospective cohort study to evaluate this hypothesis at 6 months after radiotherapy treatment. This study is planned to include 120 patients with a first head and neck cancer whit radiotherapy as part of their treatment sequence. The expected duration of inclusion is 18 months. The identification of factors affecting survival, quality of life and patient compliance is essential to determine appropriate management, particularly by creating appropriate therapeutic education programs.

This description comes directly from the study's public registry record.

Talk to the study team

Maxime Humbert, MD  ·  0231064640  ·  humbert-m@chu-caen.fr

Emmanuel Babin, PHD  ·  0231064640  ·  babin-e@chu-caen.fr

Always discuss trial participation with your own doctor first.

Locations (1)

Caen University HospitalCaen, FranceRecruiting

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Source record: clinicaltrials.gov/study/NCT05505188