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Study identifier: NCT05502523 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

The Impact of Surgical Technique on Circulating Tumor DNA in Stage I-III Non-Small Cell Lung Cancer

Condition: Lung Non-Small Cell Carcinoma · Stage I Lung Cancer AJCC v8 · Stage II Lung Cancer AJCC v8  ·  Sponsor: Thomas Jefferson University

PhaseNA
Planned participants100
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

This clinical trial compares the effect of pulmonary vein-first surgical technique to pulmonary artery-first surgical technique in decreasing circulating tumor cell deoxyribonucleic acid (ctDNA) in patients with stage I-III non-small cell lung cancer. Pulmonary vein first and pulmonary artery first surgical techniques are standard surgical techniques for the division of the blood vessels during lung resection surgery. Pulmonary vein-first surgical technique may reduce the risk of shedding tumor cells during surgery and influence long term overall survival.

This description comes directly from the study's public registry record.

Talk to the study team

Tyler Grenda, MD  ·  215-955-5562  ·  Tyler.grenda@jefferson.edu

Always discuss trial participation with your own doctor first.

Locations (4)

Abington Memorial HospitalAbington, Pennsylvania, United StatesRecruiting
Jefferson Health NortheastPhiladelphia, Pennsylvania, United StatesRecruiting
Thomas Jefferson University HospitalPhiladelphia, Pennsylvania, United StatesRecruiting
Asplundh Cancer Pavilion at Jefferson HealthWillow Grove, Pennsylvania, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT05502523