Condition: Surgical Site Infection · Microbial Colonization · Antibiotic Resistant Infection · Sponsor: Balgrist University Hospital
The perioperative antibiotic prophylaxis is evidence-based in orthopedic surgery. While its duration ranges from a single dose to three doses throughout the world, the choice of the prophylactic agents is undisputed. Worldwide, the surgeons use 1st or 2nd-generation cephalosporins (or vancomycin in some cases). However, there are particular clinical situation with a high risk of antibiotic-resistant surgical site infections (SSI); independently of the duration of adminis-tered prophylaxis. These resistant SSI's occur in contaminated wounds, or during surgery under current therapeutic antibiotics, and base on "selection" by antibiotics used for therapy or for prophylaxis.
This description comes directly from the study's public registry record.
Ilker Uçkay, Professor · ++41 44 386 37 05 · ilker.uckay@balgrist.ch
Mazda Farshad, Professor · ++ 41 44 386 30 00 · mazda.farshad@balgrist.ch
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| Balgrist University Hospital | Zurich, Switzerland | Recruiting |
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Source record: clinicaltrials.gov/study/NCT05502380