Condition: Cognitive Impairment · Sleep Quality · Sponsor: State University of New York at Buffalo
Poor sleep quality and short sleep duration may be a mechanistic component of cognitive impairment in older adults, associated with a decline in brain-derived neurotrophic factor. Increasing the availability of nicotinamide adenine dinucleotide (NAD+) with supplementation of its precursor, nicotinamide riboside (NR), a form of vitamin B3 may increase the expression of brain-derived neurotrophic factor. This study proposes to examine the benefits of NR supplementation on sleep and cognitive function in older adults with comprehensive subjective and objective measures and to explore its impacts on serum brain-derived neurotrophic factor.
This description comes directly from the study's public registry record.
Carleara Weiss, PhD, MS, RN · 7168282006 · carleara@buffalo.edu
Rebecca A Lorenz, PhD, RN · 716-829-2204 · rlorenz@buffalo.edu
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| State University of New York at Buffalo | Buffalo, New York, United States | Not Yet Recruiting |
| University at Buffalo State University of New York | Buffalo, New York, United States | Not Yet Recruiting |
| Buffalo Veteran Affairs Medical Center | Buffalo, New York, United States | Recruiting |
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Source record: clinicaltrials.gov/study/NCT05500170