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Study identifier: NCT05498792 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Study of CBL0137 in Combination With Ipilimumab and Nivolumab Therapy in Melanoma

Condition: Locally Advanced or Metastatic Melanoma  ·  Sponsor: Fox Chase Cancer Center

PhaseEARLY_Phase 1
Planned participants12
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

Phase I, open label, dose-escalation, and safety study designed to assess the safety and biologic activity of the investigational agent CBL0137 in combination with standard of care drugs, ipilimumab and nivolumab in sequential cohorts of adult patients with locally advanced and metastatic melanoma who are candidates for immune checkpoint blockade and have tumors accessible for serial biopsies.

This description comes directly from the study's public registry record.

Talk to the study team

Anthony Olszanski, MD  ·  2152141676  ·  Anthony.Olszanski@fccc.edu

Tanu Singh, PhD  ·  2152141439  ·  Tanu.Singh@fccc.edu

Always discuss trial participation with your own doctor first.

Locations (1)

Fox Chase Cancer CenterPhiladelphia, Pennsylvania, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT05498792