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Study identifier: NCT05496036 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Neoadjuvant PD-1 Blockade in Resectable Merkel Cell Carcinoma

Condition: Merkel Cell Carcinoma  ·  Sponsor: Abramson Cancer Center at Penn Medicine

PhasePhase 2
Planned participants15
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

The main purpose of this study is to determine the response of Merkel cell carcinoma to pembrolizumab before surgery and to determine whether it further reduces the risk for disease recurrence. Another purpose of this study is to look at the side effects that occur when the experimental drug pembrolizumab is given to people with Merkel cell carcinoma before and after their standard of care surgery to remove the Merkel cell carcinoma.

This description comes directly from the study's public registry record.

Talk to the study team

Lydia Giles, BSN, RN  ·  2156626389  ·  Lydia.Giles@pennmedicine.upenn.edu

John Miura, MD  ·  267-588-9179  ·  John.Miura@Pennmedicine.upenn.edu

Always discuss trial participation with your own doctor first.

Locations (1)

Penn MedicinePhiladelphia, Pennsylvania, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT05496036