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Study identifier: NCT05492708 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

The Heartland Study

Condition: Pregnancy Related · Pregnancy Complications · Birth Defect  ·  Sponsor: Heartland Health Research Alliance

PhaseN/A
Planned participants2600
Who can joinFemale, 18 Years to no upper limit
Healthy volunteersYes

About this study

The Heartland Study is a prospective, observational study that will enroll up to 2,600 pregnant participants across the Heartland States in the U.S.. The objective of the Heartland Study is to address major knowledge gaps concerning the health effects of herbicides on maternal and infant health. The study is being conducted to evaluate the associations between environmental exposures to herbicides during and after pregnancy and reproductive health outcomes. The study is measuring multiple biomarkers of herbicide exposure among pregnant Midwesterners and their partners to evaluate associations with pregnancy and childbirth outcomes, epigenetic biomarkers of exposure, and child development.

This description comes directly from the study's public registry record.

Talk to the study team

Kathleen Flannery  ·  317-880-3961  ·  kamaflan@iu.edu

Always discuss trial participation with your own doctor first.

Locations (4)

Indiana University Medical CenterIndianapolis, Indiana, United StatesRecruiting
University of Iowa Health CareIowa City, Iowa, United StatesRecruiting
Gundersen HealthLa Crosse, Wisconsin, United StatesCompleted
Marshfield ClinicMarshfield, Wisconsin, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT05492708