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Study identifier: NCT05490888 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Single and Multiple Dose Escalation of PHIN-214 in Child-Pugh A and B Liver Cirrhotics

Condition: Cirrhosis, Liver · Liver Fibrosis · Ascites Hepatic  ·  Sponsor: PharmaIN

PhasePhase 1
Planned participants74
Who can joinAll sexes, 18 Years to 75 Years
Healthy volunteersNo

About this study

This 2-part study will evaluate PHIN-214 given as a single one-time dose (Part 1) and in multiple doses (given as daily doses for 28-days) (in Part 2). Specifically, this study evaluates PHIN-214, to determine the safety, tolerability, and pharmacokinetic effects of PHIN-214, and to establish the maximum tolerated dose or optimal beneficial dose in patients with Child Pugh A and B Cirrhosis.

This description comes directly from the study's public registry record.

Talk to the study team

Cynthia C Jones  ·  206-568-1450  ·  PHIN.214001@pharmain.com

Always discuss trial participation with your own doctor first.

Locations (9)

Arizona Liver HealthChandler, Arizona, United StatesRecruiting
Southern California Research CenterCoronado, California, United StatesRecruiting
Tandem Clinical ResearchMarrero, Louisiana, United StatesRecruiting
Mayo ClinicRochester, Minnesota, United StatesRecruiting
Cleveland ClinicCleveland, Ohio, United StatesRecruiting
University of PennsylvaniaPhiladelphia, Pennsylvania, United StatesRecruiting
Methodist Health System, Dallas Medical CenterDallas, Texas, United StatesRecruiting
VA North Texas Healthcare SystemDallas, Texas, United StatesRecruiting
Texas Liver InstituteSan Antonio, Texas, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT05490888