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Study identifier: NCT05489887 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Naxitamab Added to Induction for Newly Diagnosed High-Risk Neuroblastoma

Condition: Neuroblastoma  ·  Sponsor: Giselle Sholler

PhasePhase 2
Planned participants93
Who can joinAll sexes, 12 Months to 21 Years
Healthy volunteersNo

About this study

This is a prospective, multicenter clinical trial in subjects with newly diagnosed high-risk neuroblastoma to evaluate the efficacy and safety of administering naxitamab with standard induction therapy. The initial chemotherapy will include 5 cycles of multi-agent chemotherapy. Naxitamab will be added to all 5 Induction cycles. We hypothesize that the addition of anti-GD2 therapy to induction chemotherapy will result in improved end of induction responses and improved survival.

This description comes directly from the study's public registry record.

Talk to the study team

BCC Enroll  ·  7175310003  ·  BCCEnroll@pennstatehealth.psu.edu

Always discuss trial participation with your own doctor first.

Locations (25)

University of Alabama/Children's of AlabamaBirmingham, Alabama, United StatesRecruiting
Arkansas Children's HospitalLittle Rock, Arkansas, United StatesRecruiting
UCSF Benioff Children's Hospital OaklandOakland, California, United StatesRecruiting
Rady Children's HospitalSan Diego, California, United StatesRecruiting
Connecticut Children's HospitalHartford, Connecticut, United StatesRecruiting
University of FloridaGainesville, Florida, United StatesRecruiting
Nicklaus Children's HospitalMiami, Florida, United StatesRecruiting
Arnold Palmer Hospital for ChildrenOrlando, Florida, United StatesRecruiting
Augusta University HealthAugusta, Georgia, United StatesRecruiting
Kapiolani Medical Center for Women and ChildrenHonolulu, Hawaii, United StatesRecruiting
Norton Children's Research Institute/Affiliated with University of Louisville School of MedicineLouisville, Kentucky, United StatesRecruiting
Children's Hospital and Clinics of MinnesotaMinneapolis, Minnesota, United StatesRecruiting

+ 13 more locations — full list on the registry record.

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Source record: clinicaltrials.gov/study/NCT05489887