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Study identifier: NCT05489705 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

A Prospective Registry Study to Assess Real-world Patient Characteristics, Treatment Patterns, and Longitudinal Outcomes in Patients Receiving Mavacamten and Other Treatments for Symptomatic Obstructive Hypertrophic Cardiomyopathy (Obstructive-HCM)

Condition: Obstructive Hypertrophic Cardiomyopathy  ·  Sponsor: Bristol-Myers Squibb

PhaseN/A
Planned participants1700
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

This registry evaluates patient characteristics, real-world treatment patterns, and short- and long-term outcomes in a population of patients in the United States and Europe with symptomatic obstructive hypertrophic cardiomyopathy (HCM) who are receiving mavacamten, receiving other treatment for obstructive HCM, or not receiving treatment for obstructive HCM due to intolerance or failure of prior treatment. United States Sub-Study: The purpose of this study is to evaluate the safety of mavacamten in patients with symptomatic obstructive HCM in the real-world setting. Europe Sub-Study: The purpose of this study is to evaluate the effectiveness and safety of mavacamten in patients with symptomatic obstructive HCM in the real-world setting.

This description comes directly from the study's public registry record.

Talk to the study team

BMS Clinical Trials Contact Center www.BMSClinicalTrials.com  ·  855-907-3286  ·  Clinical.Trials@bms.com

First line of the email MUST contain NCT # and Site #.

Always discuss trial participation with your own doctor first.

Locations (99)

Alaska Heart InstituteAnchorage, Alaska, United StatesRecruiting
Pima Heart and VascularTucson, Arizona, United StatesRecruiting
UAMSLittle Rock, Arkansas, United StatesRecruiting
UC San Diego School of MedicineLa Jolla, California, United StatesRecruiting
Keck School of Medicine of USC-UscLos Angeles, California, United StatesRecruiting
Stanford Health Care Hospital & ClinicsPalo Alto, California, United StatesRecruiting
University Of California San Francisco Medical CenterSan Francisco, California, United StatesRecruiting
UC Denver, AMCAurora, Colorado, United StatesRecruiting
Hartford HealthCareHartford, Connecticut, United StatesRecruiting
MedStar Washington Hospital CenterWashington D.C., District of Columbia, United StatesRecruiting
Uf Health JacksonvilleJacksonville, Florida, United StatesRecruiting
University of Hawaii Cancer CenterHonolulu, Hawaii, United StatesRecruiting

+ 87 more locations — full list on the registry record.

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Source record: clinicaltrials.gov/study/NCT05489705