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Study identifier: NCT05487612 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

MiECC Versus Conventional Cardiopulmonary Bypass in Cardiac Surgery (MiECS)

Condition: Coronary Artery Disease · Aortic Valve Stenosis · Extracorporeal Circulation; Complications  ·  Sponsor: Aristotle University Of Thessaloniki

PhaseNA
Planned participants1300
Who can joinAll sexes, 18 Years to 85 Years
Healthy volunteersNo

About this study

MiECS is one of the largest multicentre randomised controlled trials on extracorporeal circulation conducted under the auspices of Minimal Invasive Extracorporeal Technologies International Society (MiECTiS). It is designed to ultimately address the emerging effectiveness of MiECC systems in the light of modern perfusion practice worldwide. The primary hypothesis is that MiECC, as compared to conventional CPB (cCPB), reduces the proportion of patients experiencing serious perfusion-related postoperative morbidity after cardiac surgery. The study will be led by the Clinical Research Unit of the Special Unit for Biomedical Research and Education (SUBRE), Aristotle University of Thessaloniki School of Medicine in Greece (AUSoM) with Chief Investigator Professor Kyriakos Anastasiadis, who is a key-opinion-leader in the field of MiECC, founder and Executive Board of MiECTiS.

This description comes directly from the study's public registry record.

Talk to the study team

Georgios Papazisis, Assoc. Prof.  ·  +30 2310999323  ·  papazisg@auth.gr

Always discuss trial participation with your own doctor first.

Locations (13)

Perfusion Services University Health Network, Toronto General HospitalToronto, CanadaRecruiting
Department of Cardiac SurgeryCoswig, GermanyActive Not Recruiting
Department of Thoracic and Cardiovascular Surgery, University Medical Centre GoettingenGöttingen, GermanyActive Not Recruiting
Department of Cardiothoracic and Vascular Surgery, Ulm University HospitalUlm, GermanyCompleted
Cardiothoracic Department AHEPA University HospitalThessaloniki, GreeceRecruiting
Department of Cardiac Surgery GVM Anthea HospitalBari, ItalyRecruiting
Department of Cardiac Surgery GVM Maria Eleonora HospitalPalermo, ItalyActive Not Recruiting
Department of Cardiovascular Surgery, Ankara City HospitalAnkara, Turkey (Türkiye)Active Not Recruiting
Department of Cardiovascular Surgery, Izmir Bakırçay University, Faculty of MedicineIzmir, Turkey (Türkiye)Recruiting
Department of Cardiovascular Surgery, Faculty of Medicine, Recep Tayyip Erdoğan UniversityRize, Turkey (Türkiye)Recruiting
Department of Cardiac Surgery, Royal Papworth HospitalCambridge, United KingdomActive Not Recruiting
Deparment of Cardiac Surgery, Castle Hill HospitalHull, United KingdomActive Not Recruiting

+ 1 more locations — full list on the registry record.

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Source record: clinicaltrials.gov/study/NCT05487612