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Study identifier: NCT05487053 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

The Impact of Single-shot Adductor Canal Block Versus Continuous Femoral Nerve Block on Rehabilitation After Total Knee Replacement

Condition: Osteo Arthritis Knee · Gonarthrosis  ·  Sponsor: Negovsky Reanimatology Research Institute

PhaseNA
Planned participants220
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

Total knee replacement (TKR) is considered the most effective and safe method of radical treatment of late stages of knee osteoarthritis. A well-known problem of TKR is a severe postoperative pain syndrome, which is observed in more than 50% of patients. Femoral nerve block (FNB) is the "gold standard" for continuous postoperative analgesia after total knee replacement, as it is effective in reducing the frequency of use of opioid analgetics and reduce the duration of hospitalization. At the same time, the negative effect of this method is the motor blockade of the quadriceps femoris muscle which leads to functional impairment and is associated with an increased risk of falling. Adductor canal block (ACB) provides adequate analgesia comparable to femoral nerve block. Moreover, ACB doesn't affect the motor function of the quadriceps femoris muscle. The possibility of enhanced recovery after total knee replacement is the reason to compare single-shot adductor canal block and continuous femoral nerve block.

This description comes directly from the study's public registry record.

Talk to the study team

Valery Likhvantsev  ·  +79036235982  ·  lik0704@gmail.com

Levan Berikashvili  ·  +79263308968  ·  levan.berikashvili@mail.ru

Always discuss trial participation with your own doctor first.

Locations (1)

Clinical Hospital on YauzaMoscow, RussiaRecruiting

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Source record: clinicaltrials.gov/study/NCT05487053