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Study identifier: NCT05484557 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Prevention of Thromboembolism Using Apixaban vs Enoxaparin Following Spinal Cord Injury

Condition: Spinal Cord Injuries · Spinal Diseases  ·  Sponsor: Loewenstein Hospital

PhaseNA
Planned participants60
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

Currently, Enoxaparin is the usual prophylactic anticoagulant treatment at the acute and sub-acute phases of spinal cord injury (SCI). Patients at the sub-acute phase of SCI (rehabilitation) will be given either Enoxaparin 40 mg/day (control) or Apixaban 2.5-5 mg twice a day. Apixaban dose will be determined by the treating physician. Treatment will be continued for either 6 or 12 weeks following injury (for AIS grades C-D and A-B respectively). Endpoints: Venous thromboembolism will be evaluated by D-Dimer test every 2 weeks and an ultrasound doppler at the beginning and the end of the treatment. Bleeding events will be recorded and hematocrit will be monitored every two weeks.

This description comes directly from the study's public registry record.

Talk to the study team

Amiram Catz, MD PhD  ·  972-9-770-9934  ·  amiramc@clalit.org.il

Always discuss trial participation with your own doctor first.

Locations (1)

Loewenstein Rehabilitation HospitalRaanana, IsraelRecruiting

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Source record: clinicaltrials.gov/study/NCT05484557