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Study identifier: NCT05484206 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Effect of Hepatic Impairment on the Pharmacokinetics and Safety of VIR-2218 and VIR-3434

Condition: Hepatic Impairment · Cirrhosis  ·  Sponsor: Vir Biotechnology, Inc.

PhasePhase 1
Planned participants144
Who can joinAll sexes, 18 Years to 70 Years
Healthy volunteersYes

About this study

In this study, a single dose of VIR-2218 up to 200 mg SC or VIR-3434 at 300 mg SC monotherapy or a combination of VIR-2218 and VIR-3434 will be administered to assess the pharmacokinetic (PK) exposure, safety, and tolerability of VIR-2218 and VIR-3434 in participants with cirrhosis and Hepatic Impairment, defined using the Child-Pugh-Turcotte (CPT) categorization.

This description comes directly from the study's public registry record.

Talk to the study team

Contact details are listed per location below or on the registry record.

Always discuss trial participation with your own doctor first.

Locations (5)

Inland Empire Clinical TrialsRialto, California, United StatesRecruiting
Orange County Research CenterTustin, California, United StatesRecruiting
CenExel Research Centers of AmericaHollywood, Florida, United StatesWithdrawn
Floridian Clinical ResearchMiami Lakes, Florida, United StatesRecruiting
Texas Liver InstituteSan Antonio, Texas, United StatesTerminated

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Source record: clinicaltrials.gov/study/NCT05484206