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Study identifier: NCT05484128 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Lactobacillus Reuteri Strain Combination in Children Treated With PPI

Condition: Gastric Lesion · Proton Pump Inhibitor Adverse Reaction · Probiotic  ·  Sponsor: University of Bari

PhaseNA
Planned participants172
Who can joinAll sexes, 12 Months to 14 Years
Healthy volunteersNo

About this study

Probiotics might be of help in preventing dysbiosis and emergence of SIBO. Gastrus consisted of a mixture of two human strains of L. Reuteri DSM 17938 and ATCC PTA 6475; the first have extensive data supporting its use in gastric infections (18) however, it lacks the anti-inflammatory properties that have been provided by L. Reuteri DSM ATCC PTA 6475 that has excellent acid resistance and has strong anti-inflammatory properties (19); for these reasons, Gastrus is the best candidate for this indication.

This description comes directly from the study's public registry record.

Talk to the study team

ruggiero francavilla, professor  ·  0805592847  ·  ruggiero.francavilla@uniba.it

Always discuss trial participation with your own doctor first.

Locations (1)

FernandaBari, ItalyRecruiting

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Source record: clinicaltrials.gov/study/NCT05484128