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Study identifier: NCT05481723 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Lung Ultrasound-guided Hemodynamic Optimization

Condition: Lung Ultrasound · Goal Directed Therapy · Non-cardiac Surgery  ·  Sponsor: Centre Hospitalier Universitaire, Amiens

PhasePhase 3
Planned participants350
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

The formalized expert recommendation of the French Society of Anesthesia and Intensive Care recommends guiding vascular filling by measuring the stroke volume (SV) in surgical patients considered at high risk. Vascular filling should be continued in the event of preload dependence and stopped in the event of the appearance of preload independence. The aim is to avoid vascular overload due to excessive vascular filling. The application of this recommendation has resulted in a reduction in postoperative morbidity, length of hospital stay and time to return to oral feeding. The superiority of this strategy is now being questioned and the predictive indices of response to vascular filling (static and dynamic) have many limitations. In addition, none of the cardiac output monitors are the gold standard for intraoperative use. Through the study of artefacts, lung ultrasound has been gaining ground over the last twenty years, particularly in cardiology, nephrology and intensive care. By analogy with radiological B-lines, ultrasound B-lines result from the reverberation of ultrasound on the subpleural inter-lobular septa thickened by oedema. The Fluid Administration Limited by Lung Sonography (FALLS) protocol, described by Lichtenstein et al, is defined as the visualisation of new B lines during a vascular filling test. If a B-line appears in an area where it was not present during vascular filling, the most likely diagnosis is hydrostatic overload of the subpleural interstitial sep…

This description comes directly from the study's public registry record.

Talk to the study team

Stéphane BAR, DR  ·  03 22 08 79 06  ·  bar.stephane@chu-amiens.fr

Always discuss trial participation with your own doctor first.

Locations (1)

CHU AmiensAmiens, FranceRecruiting

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Source record: clinicaltrials.gov/study/NCT05481723