Condition: Solid Tumor, Adult · Solid Tumor, Childhood · Hematologic Cancer · Sponsor: Gustave Roussy, Cancer Campus, Grand Paris
This is a study to explore the phenotypic and transcriptional changes of different cellular components in the tumor following the injection of somatic cell therapy drugs. The second objective is to explore phenotypic and transcriptional changes of different cellular components in blood and bone marrow following injection of somatic cell therapy drugs.Then correlate the phenotypic and transcriptional profile of different tumor, blood and bone marrow immune populations with clinical response and/or toxicity. And to finish this study is designed in order to identify a phenotypic, transcriptional and epigenetic profile of intra-tumoral adoptive cells and correlate this profile with clinical response and/or toxicity.
This description comes directly from the study's public registry record.
Camille BIGENWALD, MD · +33 (0)1 42 11 42 29 · camille.bigenwald@gustaveroussy.fr
Cristina CASTILLA LLORENTE, MD · +33 (0)1 42 11 42 39 · cristina.castilla-llorente@gustaveroussy.fr
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| Gustave Roussy Cancer Campus Grand Paris | Villejuif, Val De Marne, France | Recruiting |
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Source record: clinicaltrials.gov/study/NCT05481502