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Study identifier: NCT05478083 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

A GnRH Agonist IN Pre-menopausal Women STudy to Treat Severe Polycystic Liver Disease

Condition: Polycystic Liver Disease · Autosomal Dominant Polycystic Kidney  ·  Sponsor: University Medical Center Groningen

PhasePhase 2
Planned participants36
Who can joinFemale, 18 Years to 45 Years
Healthy volunteersNo

About this study

Multicenter trial on the effect of the GnRH analogue leuprorelin on the growth of total liver volume in pre-menopausal women with very severe polycystic liver disease who, despite available therapy, experience growth and are heading for liver transplantation.

This description comes directly from the study's public registry record.

Talk to the study team

Ron T Gansevoort  ·  +31 50 3610923  ·  r.t.gansevoort@umcg.nl

Renée Duijzer  ·  renee.duijzer@radboudumc.nl

Always discuss trial participation with your own doctor first.

Locations (2)

RadboudumcNijmegen, Gelderland, NetherlandsNot Yet Recruiting
Groningen universitair medical centerGroningen, NetherlandsRecruiting

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Source record: clinicaltrials.gov/study/NCT05478083