Condition: Type 2 Diabetes · Sponsor: Baylor College of Medicine
Type 2 diabetes (T2D), once considered only "a disease of older ages," is now a significant public health concern in youth. Although it is characterized by insulin resistance and impaired insulin secretion, its precise etiology and pathogenesis are not yet fully understood. This study aims to (1) explore arginine metabolism in youth with T2D via safe, minimally invasive kinetic experiments using stable isotope tracers and targeted metabolomics, and (2) determine the effect of exogenous arginine administration on β-cell function in youth with T2D, potentially supporting the use of this safe, low-cost, and readily available nutrient to improve pediatric diabetes outcomes.
This description comes directly from the study's public registry record.
Mustafa Tosur, MD · 832-822-3780 · mustafa.tosur@bcm.edu
Lori Malone · 832-822-3784 · lmalone@bcm.edu
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| Texas Children's Hospital / Baylor College of Medicine | Houston, Texas, United States | Recruiting |
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Source record: clinicaltrials.gov/study/NCT05477134