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Study identifier: NCT05475925 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

A Study of DR-01 in Subjects With Large Granular Lymphocytic Leukemia or Cytotoxic Lymphomas

Condition: LGLL - Large Granular Lymphocytic Leukemia · Primary Cutaneous Gamma-Delta T-Cell Lymphoma · Primary Cutaneous CD8+ Aggressive Epidermotropic T-Cell Lymphoma  ·  Sponsor: Dren Bio

PhasePhase 1/Phase 2
Planned participants200
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

This is a multicenter, first-in-human, Phase 1/2 study to evaluate the safety, tolerability, pharmacokinetics, pharmacodynamics, and anti-tumor activity of DR-01 in adult patients with large granular lymphocytic leukemia or cytotoxic lymphomas

This description comes directly from the study's public registry record.

Talk to the study team

Dren Central Contact  ·  415-737-5277  ·  DR-01-ONC-001_inquiries@drenbio.com

Always discuss trial participation with your own doctor first.

Locations (37)

Dren Investigational SiteBirmingham, Alabama, United StatesRecruiting
Dren Investigational SiteDuarte, California, United StatesRecruiting
Dren Investigational SiteIrvine, California, United StatesRecruiting
Dren Investigational SiteRedwood City, California, United StatesRecruiting
Dren Investigational SiteNew Haven, Connecticut, United StatesRecruiting
Dren Investigational SiteTampa, Florida, United StatesRecruiting
Dren Investigational SiteBoston, Massachusetts, United StatesRecruiting
Dren Investigational Site 1New York, New York, United StatesRecruiting
Dren Investigational Site 2New York, New York, United StatesNot Yet Recruiting
Dren Investigational SiteColumbus, Ohio, United StatesRecruiting
Dren Investigational Site 2Pittsburgh, Pennsylvania, United StatesRecruiting
Dren Investigational SiteHouston, Texas, United StatesRecruiting

+ 25 more locations — full list on the registry record.

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Source record: clinicaltrials.gov/study/NCT05475925