← Eichor
Study identifier: NCT05475366 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Personalized First-line Chemotherapy Choice in Advanced Pancreatic Adenocarcinoma Using Transcriptomic Signatures

Condition: Carcinoma, Pancreatic Ductal · Prognosis  ·  Sponsor: Institut Curie

PhaseNA
Planned participants85
Who can joinAll sexes, 18 Years to 75 Years
Healthy volunteersNo

About this study

The aim of this study is to assess the clinical value of 5 transcriptomic signatures prognostic of chemotherapeutic sensitivity to improve the Objective Response Rate (ORR) of first-line (L1). Chemotherapy regimen (FOLFIRINOX vs Gem-nabP) will be selected based on transcriptomic signatures applied to the pre-therapeutic liver biopsy of newly diagnosed PDAC patients.

This description comes directly from the study's public registry record.

Talk to the study team

Cindy NEUZILLET, MD, PhD  ·  +33 (0) 6 82 55 04 92  ·  cindy.neuzillet@aphp.fr

Marie-Emmanuelle Legrier  ·  drci.promotion@curie.fr

Always discuss trial participation with your own doctor first.

Locations (7)

Hôpital BeaujonClichy, FranceRecruiting
Hôpital HENRI MONDORCréteil, FranceRecruiting
Hôpital Claude HurriezLille, FranceRecruiting
Institut Paoli-CalmettesMarseille, FranceRecruiting
CHU Robert DebréReims, FranceRecruiting
Institut CurieSaint-Cloud, FranceRecruiting
Hôpital PAUL BROUSSE 12 Avenue Paul Vaillant CouturierVillejuif, FranceRecruiting

Follow this study

Get one email when the public record changes — results posted, or the study's status changes. Nothing else, ever.

We email about this public record only. Unsubscribe anytime with one click. Never medical advice.

Is this your study? This page was generated automatically from the public registry record. Sponsors can claim it — free — to add branding and verified contact routing. Claim this page →

This page is independently generated by Eichor from the public ClinicalTrials.gov record and re-synced daily. It is not the sponsor's official website unless claimed. Nothing here is medical advice; eligibility is always determined by the study team — talk to your own doctor first.

Source record: clinicaltrials.gov/study/NCT05475366