Condition: Non Small Cell Lung Cancer · Sponsor: Konkuk University Medical Center
Complete surgical resection is the standard treatment in early-stage lung cancer. However, the patients with early resected Epidermal Growth Factor Receptor(EGFR)-mutated lung cancers have high recurrence rate. The efficacy of neoadjuvant treatment by first-generation EGFR-Tyrosine Kinase Inhibitor(TKI) has been demonstrated, however, that of the third-generation EGFR-TKI(lazertinib) has not yet been fully investigated. The aim of this study is to evaluate the efficacy of neoadjuvant Lazertinib in resectable EGFR mutation-positive NSCLC and clinical application of extracellular vesicles(EVs) based BALF liquid biopsy to identify EGFR mutation without invasive tissue biopsy.
This description comes directly from the study's public registry record.
In Ae Kim, MD. PhD. · +821035438353 · 20180618@kuh.ac.kr
Kye Young Lee, MD,PhD. · 821088963916 · kyleemd@kuh.ac.kr
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| Konkuk University Medical Center | Seoul, South Korea | Recruiting |
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Source record: clinicaltrials.gov/study/NCT05469022