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Study identifier: NCT05466786 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Distribution of the Homologous Recombination-related (HRR) Genesmutationsand HRD in Breast Cancer

Condition: Breast Cancer · HER2-low Breast Cancer  ·  Sponsor: Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University

PhaseN/A
Planned participants255
Who can joinFemale, 18 Years to 70 Years
Healthy volunteersNo

About this study

This is a cross-sectional and an observational study, investigator-initiated study in HER2-low breast cancer patients. Approximately 255 subjects with HRD (homologous recombination deficiency) assessment will be enrolled in this study to examine the distribution and features of HRD/HRR (homologous recombination repair). In this study, investigators plan to clarify the frequency of HRR/HRD in Chinese patients with HER2-low breast cancer. In addition, it is planned to investigate any association between invasive disease-free survival (iDFS)/overall survival (OS) and HRD/HRR in HER2-low breast cancer patients.

This description comes directly from the study's public registry record.

Talk to the study team

Gong Chang, doctor  ·  02034070499  ·  changgong282@163.com

Always discuss trial participation with your own doctor first.

Locations (1)

Sun Yat-Sen Memorial Hospital of Sun Yat-Sen UniversityGuangzhou, Guangdong, ChinaRecruiting

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Source record: clinicaltrials.gov/study/NCT05466786