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Study identifier: NCT05462106 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

A Study to Assess the Effects of ACI-24.060 in Alzheimer's Disease and in Down Syndrome (ABATE Study)

Condition: Amyloid Plaque · Beta-Amyloid · DSAD  ·  Sponsor: AC Immune SA

PhasePhase 1/Phase 2
Planned participants304
Who can joinAll sexes, 35 Years to 85 Years
Healthy volunteersNo

About this study

The purpose of this study is to assess the safety, tolerability, immunogenicity and pharmacodynamic effects of ACI-24.060 in subjects with prodromal Alzheimer's disease and in non-demented adults with Down syndrome.

This description comes directly from the study's public registry record.

Talk to the study team

Olivier Sol, MD  ·  +41 21 345 9121  ·  clinicaltrials@acimmune.com

Benedicte Le  ·  +41 21 345 9121  ·  clinicaltrials@acimmune.com

Always discuss trial participation with your own doctor first.

Locations (26)

Barrow Neurological InstitutePhoenix, Arizona, United StatesWithdrawn
K2 Medical Research The Villages LLCLady Lake, Florida, United StatesRecruiting
Charter Research, LLCOrlando, Florida, United StatesRecruiting
Headlands Horizons LLCOrlando, Florida, United StatesNot Yet Recruiting
Charter Research, LLCThe Villages, Florida, United StatesRecruiting
Indiana University / IU HealthIndianapolis, Indiana, United StatesActive Not Recruiting
University of Kansas Medical Center Research InstituteFairway, Kansas, United StatesActive Not Recruiting
Massachusetts General HospitalBoston, Massachusetts, United StatesActive Not Recruiting
The Washington UniversitySt Louis, Missouri, United StatesActive Not Recruiting
Flourish ResearchMatthews, North Carolina, United StatesNot Yet Recruiting
Neurology Clinical, P.C.Cordova, Tennessee, United StatesRecruiting
Vanderbilt University Medical CenterNashville, Tennessee, United StatesActive Not Recruiting

+ 14 more locations — full list on the registry record.

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Source record: clinicaltrials.gov/study/NCT05462106