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Study identifier: NCT05459233 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Valve Hemodynamic Optimization Based on Doppler-Echocardiography vs Catheterization Measurements Following ViV TAVR

Condition: Aortic Valve Stenosis · Aortic Valve Regurgitation · Prosthesis Failure  ·  Sponsor: Institut universitaire de cardiologie et de pneumologie de Québec, University Laval

PhaseNA
Planned participants310
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

Data on valve performance following ViV-TAVR has usually been obtained with the use of Doppler-echocardiography. However, some reports have shown significant discordances in the evaluation of mean transvalvular gradient between echocardiography and catheterization, with an overestimation of the real gradient with echo (vs. cath) in most cases. Thus, the incidence of procedural-device failure may be lower than that reported in the ViV-TAVR literature,

This description comes directly from the study's public registry record.

Talk to the study team

Josep Rodés-Cabau, MD  ·  418-656-8711  ·  josep.rodes@criucpq.ulaval.ca

Emilie Pelletier Beaumont, MSc  ·  418-656-8711  ·  emilie.pelletier-beaumont@criucpq.ulaval.ca

Always discuss trial participation with your own doctor first.

Locations (7)

University of CaliforniaSan Francisco, California, United StatesNot Yet Recruiting
South Broward Hospital Disctrict D/B/A Memorial Healthcare SystemHollywood, Florida, United StatesRecruiting
William Beaumont HospitalRoyal Oak, Michigan, United StatesRecruiting
Mayo ClinicRochester, Minnesota, United StatesRecruiting
St-Joseph's Health INCSyracuse, New York, United StatesNot Yet Recruiting
The Christ Hospital Health NetworkCincinnati, Ohio, United StatesRecruiting
IUCPQQuébec, Quebec, CanadaRecruiting

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Source record: clinicaltrials.gov/study/NCT05459233