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Study identifier: NCT05459116 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Visualization of Inspiratory Effort and Respiratory Mechanics to Promote Lung- and Diaphragm Protective Ventilation

Condition: Respiratory Muscles · Respiration, Artificial · Respiratory Function Tests  ·  Sponsor: University Hospital, Antwerp

PhaseNA
Planned participants150
Who can joinAll sexes, 29 Days to no upper limit
Healthy volunteersNo

About this study

This is a multicentre prospective cohort trial in adult and pediatric ICU patients. The investigators will measure the effect of a patient's inspiratory effort during mechanical ventilation on the lungs and diaphragm. The investigators will daily (for a maximum of 8 days) measure esophageal pressures with a balloon catheter to quantify inspiratory effort and respiratory muscle function, and perform daily ultrasound measurements of the diaphragm and the lungs. The investigators hypothesize that a small inspiratory effort will result in the preservation of diaphragm function and have no adverse effect on lung function.

This description comes directly from the study's public registry record.

Talk to the study team

Vertongen  ·  +323 821 44 04  ·  icu-research@uza.be

Marquez  ·  +323 821 36 35  ·  inzo@uza.be

Always discuss trial participation with your own doctor first.

Locations (3)

Antwerp University Hospital (UZA)Edegem, Antwerp, BelgiumRecruiting
University Hospital Leuven (UZL)Leuven, BelgiumRecruiting
The Hospital for Sick Children (SickKids)Toronto, Ontario, CanadaRecruiting

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Source record: clinicaltrials.gov/study/NCT05459116