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Study identifier: NCT05456256 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

A Study of LP-300 With Carboplatin and Pemetrexed in Never Smokers With Advanced Lung Adenocarcinoma

Condition: Adenocarcinoma of Lung · Carcinoma, Non-Small-Cell Lung  ·  Sponsor: Lantern Pharma Inc.

PhasePhase 2
Planned participants90
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

The goal of this clinical trial is to determine clinical advantages for LP-300 in combination with carboplatin and pemetrexed in the never smoker patient population. The primary objectives of this study are to determine progression-free survival (PFS) and overall survival (OS) in the study-defined patient population when LP-300 is co-administered with the standard of care chemotherapy drugs carboplatin and pemetrexed compared to carboplatin and pemetrexed alone. This has been designed as a multicenter, open label, phase II trial with 90 patients to be enrolled in the United States.

This description comes directly from the study's public registry record.

Talk to the study team

Sandra Sinclair  ·  832.622.1699  ·  sandra@lanternpharma.com

Always discuss trial participation with your own doctor first.

Locations (16)

Precision NextGen Oncology and Research CenterBeverly Hills, California, United StatesRecruiting
Los Angeles Cancer NetworkFountain Valley, California, United StatesRecruiting
Cancer and Blood Specialists ClinicLos Alamitos, California, United StatesSuspended
Fox Chase Cancer CenterPhiladelphia, Pennsylvania, United StatesRecruiting
UT Southwestern Medical CenterDallas, Texas, United StatesRecruiting
Inova Fairfax HospitalFairfax, Virginia, United StatesRecruiting
Hokkaido Cancer CenterSapporo, Hokkaido, JapanActive Not Recruiting
Kanagawa Cancer Center HospitalYokohama, Kanagawa, JapanActive Not Recruiting
Tohoku University HospitalSendai, Miyagi, JapanActive Not Recruiting
Okayama University HospitalOkayama, Okayama-ken, JapanActive Not Recruiting
National Cancer Center HospitalChuo-ku, Tokyo, JapanActive Not Recruiting
National Taiwan University Hospital Hsin-Chu BranchHsinchu, TaiwanRecruiting

+ 4 more locations — full list on the registry record.

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Source record: clinicaltrials.gov/study/NCT05456256