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Study identifier: NCT05453019 Synced from ClinicalTrials.gov · July 28, 2026
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Effects of CI on Tinnitus and Its Symptoms

Condition: Tinnitus  ·  Sponsor: Chinese PLA General Hospital

PhaseNA
Planned participants200
Who can joinAll sexes, 16 Years to 90 Years
Healthy volunteersYes

About this study

Abnormal activity in the central auditory system is the cause of subjective experience of tinnitus. Electrical stimulation can inhibit the abnormal activity of auditory related neurons in patients with tinnitus. In recent years, the application of electrical stimulation in the treatment of tinnitus is a hot research topic, and has made some progress. However, its treatment is still in the discussion stage, and there is no best scheme suitable for clinical practice. At present, scholars have found that cochlear electrode stimulation can inhibit tinnitus, but its mechanism is not clear. It is difficult to locate the origin of tinnitus, and the location of electrode stimulation and stimulation parameters still need to be further optimized. Because the implanted part of the cochlear implant contains magnets, the patients cannot perform functional MRI. However, the prevalence of tinnitus in this group is very high (67.0\~100.0%, with an average of 80.0%), so it is of great value and significance to study the effect of tinnitus treatment in such patients. In this study, a new clinical electroencephalogram (EEG) technique was used to make up for the lack of MRI imaging in patients with electrode implantation. EEG analyzes the functional connection of different brain regions through EEG test electrodes, uses the traceability function of EEG software to locate the location of tinnitus, analyzes the process of tinnitus inhibition by electrical stimulation, and explains the mechanism of…

This description comes directly from the study's public registry record.

Talk to the study team

QIAN WANG, M.S.  ·  +8618211068103  ·  only_elizabeth@126.com

Shi m Yang  ·  01068159050  ·  yangsm301@263.net

Always discuss trial participation with your own doctor first.

Locations (1)

Qian WangBeijing, France, ChinaRecruiting

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Source record: clinicaltrials.gov/study/NCT05453019