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Study identifier: NCT05451251 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Deep Brain Stimulation for Refractory Trigeminal Neuralgia with a Pontine Lesion

Condition: Trigeminal Neuralgia  ·  Sponsor: Université de Sherbrooke

PhasePhase 1
Planned participants6
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

The aim of this study is to assess the feasibility of deep brain stimulation for refractory trigeminal neuralgia due to a pontine lesion, as is usually seen in the context of multiple sclerosis. These patients usually have severe intractable facial pain and current medical and surgical options generally fail to achieve long lasting pain relief. Hoping to improve pain control in this population, the investigators of this trial propose a novel technique consisting of implanting a deep brain stimulation lead within the pontine lesion to modulate the generation of pain signals.

This description comes directly from the study's public registry record.

Talk to the study team

Christian Iorio-Morin, MD, PhD, FRCS(C)  ·  819-346-1110  ·  Christian.Iorio-Morin@usherbrooke.ca

Always discuss trial participation with your own doctor first.

Locations (1)

Centre Hospitalier Universitaire de Sherbrooke (CHUS)Sherbrooke, Quebec, CanadaRecruiting

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Source record: clinicaltrials.gov/study/NCT05451251