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Study identifier: NCT05450185 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Filter Lifespan in Continuous Renal Replacement Therapy

Condition: Critically Ill · Continuous Renal Replacement Therapy · Infections  ·  Sponsor: University Hospital Muenster

PhaseN/A
Planned participants600
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

The only supportive therapy for patients with AKI is renal replacement therapy (RRT). In the ICU setting, continuous RRT (CRRT) is mostly favored. In a post-hoc analysis of the RICH trial (regional citrate versus systemic heparin anticoagulation for CRRT in critically ill patient with AKI), it was shown that the filter life span is associated with an increased rate of new infection and that the type of anticoagulants did not directly affect infection rate. The mechanisms of this infection rate is unknown.

This description comes directly from the study's public registry record.

Talk to the study team

Alexander Zarbock, MD  ·  +49-251-8347252  ·  zarbock@uni-muenster.de

Melanie Meersch-Dini, MD  ·  +49-251-47255

Always discuss trial participation with your own doctor first.

Locations (5)

Univ.-Klinik InnsbruckInnsbruck, AustriaRecruiting
Universidade de São PauloSão Paulo, BrazilRecruiting
Universitätsklinikum Erlangen-Nürnberg, Abteilung für Nephrologie und HypertensiologieErlangen, GermanyRecruiting
Kliniken Maria Hilf, Klinik für Anästhesiologie und Operative IntensivmedizinMönchengladbach, GermanyRecruiting
University Hospital MuensterMünster, GermanyRecruiting

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Source record: clinicaltrials.gov/study/NCT05450185