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Study identifier: NCT05446545 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Bespoke ctDNA Assay for Recurrence and Treatment Response Monitoring in Advanced Epithelial Ovarian Cancer

Condition: Ovarian Cancer  ·  Sponsor: Fudan University

PhaseN/A
Planned participants139
Who can joinFemale, 18 Years to 70 Years
Healthy volunteersNo

About this study

This prospective observational study is to assess the dynamics of circulating tumor DNA (ctDNA) in patients with advanced epithelial ovarian cancer (EOC) undergoing surgery, adjuvant chemotherapy, followed by poly adenosine diphosphate-ribose polymerase (PARP) inhibitors until disease progression or the end of the study. All patients will be closely monitored throughout the course of disease by a tumor-informed bespoke ctDNA assay as well as traditional methods of surveillance, such as CA125 and imaging. This study may provide preliminary evidence for ctDNA-guided treatment decisions in future clinical practice.

This description comes directly from the study's public registry record.

Talk to the study team

Hao Wen, MD  ·  +86-021-64175590  ·  wenhao@shca.org.cn

Always discuss trial participation with your own doctor first.

Locations (1)

Hao WenShanghai, Shanghai Municipality, ChinaRecruiting

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Source record: clinicaltrials.gov/study/NCT05446545