Condition: Psychotic Disorders · Cannabis Use Disorder · Cannabis Dependence · Sponsor: Douglas Mental Health University Institute
Cognitive impairment is well established in people with psychosis and is associated with cannabis use. The current study will investigate the neurobiological basis of cognitive change associated with 28-days of cannabis abstinence in people with psychosis and non-psychiatric controls with cannabis use. Participants will be randomized to a cannabis abstinent group or a non-abstinent control group and will undergo magnetic resonance imaging at baseline and following 28-days of abstinence. This study will help characterize the neuropathophysiological processes underlying cognitive dysfunction associated with cannabis use and its recovery which may guide the development of novel interventions for problematic cannabis use.
This description comes directly from the study's public registry record.
Charlene Osei-Afrifa · (514) 761-6131 · aimh.research@gmail.com
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| Douglas Mental Health University Institute | Montreal, Quebec, Canada | Recruiting |
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Source record: clinicaltrials.gov/study/NCT05445180