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Study identifier: NCT05445063 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Safety and Efficacy of Autologous Transplantation of iPSC-RPE in the Treatment of Macular Degeneration

Condition: Macular Degeneration  ·  Sponsor: Beijing Tongren Hospital

PhasePhase 1
Planned participants10
Who can joinAll sexes, 50 Years to 75 Years
Healthy volunteersNo

About this study

This project intends to perform autologous transplantation of induced pluripotent stem cell-derived retinal pigment epithelium (iPSC-RPE). The clinical-grade RPE will be transplanted into subretinal space to treat refractory age-related macular degeneration. The efficacy and safety of RPE transplants to treat macular degeneration will be monitored and analyzed with results from EDTRS, BCVA, OCT, ERG, microperimetry, and fluorescein angiography, before and after the treatment.

This description comes directly from the study's public registry record.

Talk to the study team

Xiaohui Zhang  ·  +0086-(010)58265915  ·  zhangxh711@126.com

Always discuss trial participation with your own doctor first.

Locations (1)

Beijing Tongren Hospitol,Capital Medical UniversityBeijing, Beijing Municipality, ChinaRecruiting

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Source record: clinicaltrials.gov/study/NCT05445063