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Study identifier: NCT05443516 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Disease Activity Biomarkers in Patients With Systemic Lupus Erythematosus

Condition: Lupus Nephritis  ·  Sponsor: Cliniques universitaires Saint-Luc- Université Catholique de Louvain

PhaseN/A
Planned participants250
Who can joinAll sexes, 18 Years to 70 Years
Healthy volunteersNo

About this study

The aim of this research project is to better understand the origin and clinical significance of two lupus-specific "genetic signatures" (IFN signature and plasma cell signature) in patient subgroups with well-defined clinical characteristics. Our aim is to correlate these genetic signatures with cell activation profiles and the production of specific cytokines in different populations from whole blood and in short-term cultures of these circulating cells.

This description comes directly from the study's public registry record.

Talk to the study team

Frédéric Houssiau, Pr  ·  +32 02 764 53 90  ·  frederic.houssiau@uclouvain.be

Farah Tamirou, Pr  ·  +32 02 764 53 87  ·  farah.tamirou@uclouvain.be

Always discuss trial participation with your own doctor first.

Locations (1)

Cliniques universitaires Saint-LucBrussels, BelgiumRecruiting

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Source record: clinicaltrials.gov/study/NCT05443516