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Study identifier: NCT05442710 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Recovery From Acute Immune Failure in Septic Shock by Immune Cell Extracorporeal Therapy

Condition: Sepsis, Severe  ·  Sponsor: Artcline GmbH

PhasePhase 2
Planned participants142
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

Evaluation of a novel therapy approach for severe sepsis patients. Subjects randomized into the treatment arm receive treatment with an immune cell perfusion system on top of standard care. This may contribute to the improvement of the impaired organ function of septic shock patients by assisting the impaired immune system (immune competence enhancement = ARTICE)

This description comes directly from the study's public registry record.

Talk to the study team

Jens Altrichter, MD  ·  +49 381-440-703  ·  jens.altrichter@artcline.de

Erdmann J Zippel, RN  ·  *4915772371146  ·  erdmann.zippel@artcline.de

Always discuss trial participation with your own doctor first.

Locations (20)

Universitätsklinikum Freiburg, Interdisziplinäre Medizinische Intensivtherapie (IMIT)Freiburg im Breisgau, Baden-Wurttemberg, GermanyWithdrawn
Universitätsklinikum Regensburg, Klinik für AnästhesiologieRegensburg, Bavaria, GermanyRecruiting
Universitätsklinikum Bonn, Klinik und Poliklinik für Anästhesiologie und Operative IntensivmedizinBonn, North Rhine-Westphalia, GermanyRecruiting
Universitätsklinikum Köln, Klinik für Anästhesiologie und Operative IntensivmedizinCologne, North Rhine-Westphalia, GermanyRecruiting
Helios Klinikum AueAue, Saxony, GermanyRecruiting
Universitätsklinikum Leipzig, Klinik und PK für Anästhesiologie und IntensivtherapieLeipzig, Saxony, GermanyRecruiting
Universitätsklinikum Halle (Saale), Universitätsklinik für Anästhesiologie und Operative IntensivmedizinHalle, Saxony-Anhalt, GermanyRecruiting
UNIVERSITÄTSKLINIKUM Schleswig-Holstein Campus KielKiel, Schleswig-Holstein, GermanyRecruiting
Charité Berlin, Klinik mit Schwerpunkt Nephrologie und internistische IntensivmedizinBerlin, GermanyRecruiting
Klinikum Braunschweig, Medizinische Klinik VBraunschweig, GermanyRecruiting
Universitätsklinikum Essen, Klinik für NephrologieEssen, GermanyRecruiting
University Hospital Frankfurt, Department of Anaesthesiology, Intensive Care Medicine and Pain TherapyFrankfurt, GermanyNot Yet Recruiting

+ 8 more locations — full list on the registry record.

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Source record: clinicaltrials.gov/study/NCT05442710