← Eichor
Study identifier: NCT05442060 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

To Evaluate OBI-833/OBI-821 in Combination With First-Line Erlotinib in Patients With EGFR-Mutated, Globo H-Positive, Locally Advanced or Metastatic Non-Small Cell Lung Cancer

Condition: Non-small Cell Lung Cancer  ·  Sponsor: OBI Pharma, Inc

PhasePhase 2
Planned participants60
Who can joinAll sexes, 20 Years to no upper limit
Healthy volunteersNo

About this study

This study is a randomized, active control, open-label, phase 2 trial. Erlotinib-treated NSCLC patients will be screened for Globo H, and only Globo H+ (H score ≥ 100) subjects are eligible for the study. Eligible subjects who have been treated with 3±1 months of first-line erlotinib and have achieved stable disease (SD) or partial response (PR) status will be randomized in the ratio of 1:1 to receive erlotinib alone or erlotinib plus OBI-833/OBI-821 therapy.

This description comes directly from the study's public registry record.

Talk to the study team

Anna Hu  ·  886-2-27866589  ·  annahu@obipharma.com

Lance Ou  ·  886-2-27866589  ·  lou@obipharma.com

Always discuss trial participation with your own doctor first.

Locations (7)

Taipei Veterans General HospitalTaipei, Beitou District, TaiwanRecruiting
National Taiwan University Cancer CenterTaipei, Da'an Dist., TaiwanRecruiting
Linkou Chang Gung Memorial HospitalTaoyuan, Guishan Dist., TaiwanRecruiting
Tri-Service General HospitalTaipei, Neihu District, TaiwanRecruiting
Shuang Ho HospitalNew Taipei City, Zhonghe District, TaiwanRecruiting
National Taiwan University HospitalTaipei, Zhongzheng Dist., TaiwanRecruiting
Taichung Veterans General HospitalTaichung, TaiwanRecruiting

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Source record: clinicaltrials.gov/study/NCT05442060