Condition: Heart Failure With Preserved Ejection Fraction (HFpEF) · Sponsor: Manchester University NHS Foundation Trust
Heart failure occurs when the heart is no longer able to pump blood around the body properly. It can cause breathlessness, swollen feet and ankles, and tiredness. In about half of patients with heart failure, one measure of the heart's pumping function, called the 'ejection fraction', is normal. This type of heart failure is called heart failure with preserved ejection fraction, or HFpEF. HFpEF remains poorly understood. It is not clear why some people develop HFpEF, or what determines the severity of the condition. Treatment options may be limited. UK HFpEF is a study that aims to gain a better understanding of why people develop HFpEF, develop better tests to diagnosis it, identify and test new treatments, and follow the health of the people taking part over many years.
This description comes directly from the study's public registry record.
Fardad Soltani, MBChB MRCP · 0161 291 3223 · fardad.soltani@mft.nhs.uk
Lucy Priestner · 0044 161 291 3244 · lucy.priestner@mft.nhs.uk
Always discuss trial participation with your own doctor first.
| Cwm Taf Morgannwg University Health Board | Abercynon, United Kingdom | Recruiting |
| Buckinghamshire Healthcare NHS Trust | Aylesbury, United Kingdom | Recruiting |
| University Hospitals Birmingham NHS Foundation Trust | Birmingham, United Kingdom | Recruiting |
| Broomfield Hospital | Chelmsford, United Kingdom | Recruiting |
| NHS Tayside | Dundee, United Kingdom | Recruiting |
| Glasgow Royal Infirmary | Glasgow, United Kingdom | Recruiting |
| West Suffolk NHS Foundation Trust | Ipswich, United Kingdom | Recruiting |
| Kettering General Hospital | Kettering, United Kingdom | Recruiting |
| Leeds Teaching Hospitals NHS Trust | Leeds, United Kingdom | Recruiting |
| University Hospitals of Leicester NHS Foundation Trust | Leicester, United Kingdom | Recruiting |
| Barnet Hospital | London, United Kingdom | Recruiting |
| Guys and St. Thomas' NHS Foundation Trust | London, United Kingdom | Recruiting |
+ 14 more locations — full list on the registry record.
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Source record: clinicaltrials.gov/study/NCT05441839