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Study identifier: NCT05433142 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Study of XmAb®819 in Subjects With Advanced Clear Cell Renal Cell Carcinoma

Condition: Clear Cell Renal Cell Carcinoma  ·  Sponsor: Xencor, Inc.

PhasePhase 1
Planned participants307
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

The purpose of this study is to assess the safety and tolerability of XmAb®819 administered intravenous (IV) or subcutaneous (SC) in subjects with relapsed or refractory clear cell renal cell carcinoma and to identify the minimum safe and biologically active dose and the recommended dose (RD).

This description comes directly from the study's public registry record.

Talk to the study team

Chet Bohac, MD  ·  819-01info@xencor.com

Lisa Finnigan  ·  819-01info@xencor.com

Always discuss trial participation with your own doctor first.

Locations (26)

Xencor Investigative SitePhoenix, Arizona, United StatesRecruiting
Xencor Investigative SiteDuarte, California, United StatesRecruiting
Xencor Investigative SiteSacramento, California, United StatesRecruiting
Xencor Investigative SiteNew Haven, Connecticut, United StatesRecruiting
Xencor Investigative SiteJacksonville, Florida, United StatesRecruiting
Xencor Investigative SiteAtlanta, Georgia, United StatesRecruiting
Xencor Investigative SiteChicago, Illinois, United StatesRecruiting
Xencor Investigative SiteChicago, Illinois, United StatesRecruiting
Xencor Investigative SiteLouisville, Kentucky, United StatesRecruiting
Xencor Investigative SiteRochester, Minnesota, United StatesRecruiting
Xencor Investigative SiteNew Brunswick, New Jersey, United StatesRecruiting
Xencor Investigative SiteNew York, New York, United StatesRecruiting

+ 14 more locations — full list on the registry record.

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Source record: clinicaltrials.gov/study/NCT05433142