Condition: Non-small Cell Lung Cancer · Sponsor: Tang-Du Hospital
In this single-arm, phase II clinical trial, patients with resectable, EGFR-mutated, stage II-IIIB NSCLC received neoadjuvant therapy with furmonertinib (oral, 80 mg once daily, stopped 1 week preoperatively) in combination with platinum-based doublet chemotherapy every 3 weeks for a total of 3 cycles. Surgery was performed 4-6 weeks after chemotherapy. The primary endpoint was objective response rate (ORR). Secondary endpoints included the pathological complete response (pCR) rate, major pathological response (MPR) rate, TNM downstaging rate, R0 resection rate, EFS, overall survival (OS), drug safety and surgical complications.
This description comes directly from the study's public registry record.
Jie Lei, MD · 15094079004 · leijiemd@163.com
Always discuss trial participation with your own doctor first.
| Tangdu Hospital | Xi'an, Shannxi, China | Recruiting |
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Source record: clinicaltrials.gov/study/NCT05430802