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Study identifier: NCT05425355 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Intravenous vs Oral Acetaminophen in Postoperative Hip Fracture Adult Patients

Condition: Hip-fracture · Surgery  ·  Sponsor: University Health Network, Toronto

PhasePhase 4
Planned participants42
Who can joinAll sexes, 60 Years to no upper limit
Healthy volunteersNo

About this study

The INTACT-HIP trial study will evaluate feasibility of conducting a randomized, double-blinded controlled trial comparing postoperative treatment with intravenous (IV) acetaminophen versus oral acetaminophen, in older adults undergoing hip fracture surgery. The results of this feasibility trial will be used to inform designing a larger, multi-center, randomized controlled trial to assess the efficacy of IV acetaminophen compared to oral acetaminophen to reduce delirium and improve other clinical and patient-centered outcomes after hip fracture surgery. It will randomize 42 older adults to receive either oral or IV acetaminophen after hip fracture surgery.

This description comes directly from the study's public registry record.

Talk to the study team

Laurentia Enesi  ·  416-603-5800  ·  laurentia.enesi@uhn.ca

Aparna P Saripella  ·  416-603-5800  ·  aparna.saripella@uhn.ca

Always discuss trial participation with your own doctor first.

Locations (1)

Toronto Western Hospital (UHN)Toronto, Ontario, CanadaRecruiting

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Source record: clinicaltrials.gov/study/NCT05425355