← Eichor
Study identifier: NCT05423665 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Speckle Tracking Echocardiography as a Tool for Early Diagnosis of Impaired Fetal Growth Twin Pregnancies

Condition: Fetal Growth Restriction · Cardiac Remodeling, Ventricular · Placental Insufficiency  ·  Sponsor: University Hospital, Ghent

PhaseN/A
Planned participants360
Who can joinFemale, 18 Years to 45 Years
Healthy volunteersNo

About this study

In this project there are 2 time points during the pregnancy included, namely at 21 weeks and 30 weeks of gestation, to measure the predictive values of FGR, strain and strain rate. The fetal growth parameters will be collected at the same time points, to define the growth (differences) throughout gestation of both fetuses. A maternal blood sample will be taken at 21 weeks of gestation to identify the level of exposure to air pollution (black carbon) and the level of biochemical markers of placental dysfunction. Doppler ultrasounds will be used for antenatal identification of placenta insufficiency. At birth, umbilical cord blood and the placenta will be collected. The placenta will be examined, to identify morphological findings which are associated with FGR. The umbilical cord blood and placental biopsy will be used for the level of exposure to air pollution and the level of oxidative stress. One to three days after birth, neonatal strain and strain rate will be measured to define postnatal cardiac remodeling as well as the neonatal blood pressure as cardiovascular risk factor.

This description comes directly from the study's public registry record.

Talk to the study team

Eline Meireson  ·  0032 9 332 78 17  ·  eline.meireson@uzgent.be

Always discuss trial participation with your own doctor first.

Locations (3)

Ghent University HospitalGhent, BelgiumRecruiting
Universitair ziekenhuis LeuvenLeuven, BelgiumNot Yet Recruiting
Maxima medical centerEindhoven, NetherlandsNot Yet Recruiting

Follow this study

Get one email when the public record changes — results posted, or the study's status changes. Nothing else, ever.

We email about this public record only. Unsubscribe anytime with one click. Never medical advice.

Is this your study? This page was generated automatically from the public registry record. Sponsors can claim it — free — to add branding and verified contact routing. Claim this page →

This page is independently generated by Eichor from the public ClinicalTrials.gov record and re-synced daily. It is not the sponsor's official website unless claimed. Nothing here is medical advice; eligibility is always determined by the study team — talk to your own doctor first.

Source record: clinicaltrials.gov/study/NCT05423665